Games Done Quick is a speedrunning-for-charity event that's been going on for a fair few years now, and this year had at least a couple of Lucasarts adventures on the roster. Here's someone razzing their way through COMI:
There was also the Maniac Mansion NES run (on Twitch or Youtube).
Idon't think I've ever seen the NES version of MM, seems like it'd be hard to control with a controller, and even the runner seems to have some difficulty with it.